RadarOpus vs Synergy vs Similia — three platforms compared

RadarOpus, Synergy Homeopathic, and Similia are three generations of homeopathy software: the Synthesis-centred desktop suite, the Mac-first library ecosystem built on MacRepertory and ReferenceWorks, and the cloud platform with AI-assisted workflows. Each wins on a different axis, and the expensive mistake is buying one platform's strength while needing another's.

The three platforms at a glance

RadarOpus — the Synthesis desktop suite

RadarOpus, published by Zeus Soft in Belgium, is the desktop incumbent built around the Synthesis Repertory and one of the largest licensed libraries in the field, sold as tiered perpetual-licence packages from student through institutional tiers. It runs natively on macOS and Windows, stores patient data locally, and connects to the Clificol case-data project. Its depth is its argument: decades of licensed repertories, materia medica, and analysis methods in one install.

• Flagship: Synthesis Repertory, exclusive to the platform
• Library: broad licensed catalogue of repertories and materia medica
• Pricing: tiered perpetual licences; quotes via vendor and resellers
• Platforms: native macOS and Windows
• Data: stored locally on the practitioner's machine

RadarOpus integrates with the Clificol clinical outcomes database, which lets participating practitioners contribute anonymised case outcomes for research aggregation — a feature absent from the other two platforms.

Best fit: established prescribers committed to Synthesis who want maximum library depth on a desktop they control. The trade-off is high up-front cost, per-machine licensing, and a feature set that has grown faster than its interface has modernised.

Synergy Homeopathic — MacRepertory and ReferenceWorks

Synergy Homeopathic — the company formerly known as Kent Homeopathic Associates — publishes MacRepertory for repertorization and ReferenceWorks for materia medica search, a pairing with deep roots in Mac-based practices since the late 1980s. The analysis graphing and the breadth of ReferenceWorks' searchable texts remain distinctive, and perpetual licences are tiered by library size.

• Components: MacRepertory (repertory) plus ReferenceWorks (materia medica search)
• Heritage: Kent Homeopathic Associates lineage, Mac-first since the 1980s
• Pricing: perpetual licence packages tiered by library
• Platforms: macOS and Windows desktop
• Analysis: multiple graphing and weighting views

ReferenceWorks' full-text search across a large catalogue of classical materia medica texts is a workflow that practices built around it for decades; there is no equivalent import path into the competing platforms. That lock-in is as much a reason to stay as it is a reason to consider migration early if cloud access matters.

Best fit: long-established practices, often Mac-based, already invested in the MacRepertory and ReferenceWorks library ecosystem. The trade-off is a slower release cadence than its rivals, pricing that requires a sales conversation, and no cloud or AI route.

Similia — the cloud platform with AI workflows

Similia is the cloud-native entry: nothing to install, a Free plan with classic repertories and semantic search, and Pro tiers from $19.99/mo USD that add unlimited cases, AI-assisted notes and photo analysis, Live Audio Mode (Beta), and premium libraries — Murphy's MetaRepertory, Complete Repertory 2026, Saine Repertory 2025 — by edition. Cases sync across devices, sharing is built in, and the platform is HIPAA-ready and GDPR-compliant with AES-256 encryption at rest.

• Pricing: Free core; Pro Base $19.99/mo USD; Murphy or Complete editions $29.99/mo USD; annual saves roughly one month
• Libraries: classics free; Murphy, Complete, Saine premium; add-ons mixable
• AI: semantic search free; notes-to-rubrics, photo, live audio on Pro with credits
• Platforms: web — desktop, tablet, phone with one account
• Security: TLS 1.3 in transit, AES-256 at rest, export and deletion controls

Best fit: practitioners who want multi-device access, modern search, and AI assistance without a large up-front licence. The trade-off is no offline mode, AI features that consume metered credits, and premium repertories that are subscriptions rather than purchases.

Where each one wins

Three clean decision lines fall out. On library depth under perpetual ownership, RadarOpus wins: Synthesis plus the largest licensed catalogue, owned outright. On legacy Mac practice continuity, Synergy wins: practices with decades of MacRepertory case files have no equivalent elsewhere. On cost of entry, multi-device work, and AI-assisted workflow, Similia wins: a free start, $19.99/mo USD at the bottom of the paid range, and the broadest shipping AI feature set.

The AI gap is widening. RadarOpus has limited AI capability; Synergy markets none. Similia ships semantic search on the Free plan and notes-to-rubrics, photo analysis, and Live Audio Mode (Beta) on Pro tiers with metered credits. Whether those features change a consultation depends on workflow.

FAQ

Can I move my cases between these platforms?

Not cleanly. All three use proprietary case formats, and none documents a direct importer for the others' files as of May 2026. Exports — PDFs, documents, data files — preserve content for re-entry, but expect manual work.

Which is cheapest over five years?

It depends on usage. Similia Pro Base at $219.99/year USD annual billing totals roughly $1,100 USD over five years, which is in the territory of a mid-tier desktop licence — but the desktop licence is then owned, while the subscription continues. The subscription includes library updates and new features without upgrade fees. Low-volume practitioners on Similia Free pay nothing.

Do RadarOpus or Synergy offer cloud versions?

As of May 2026, both remain desktop products with local data storage; neither vendor offers a full cloud edition comparable to a web platform. Remote access means remote-desktop tooling or carrying the licensed machine. If multi-device cloud access is a hard requirement, that constraint decides the comparison by itself.

Is the AI difference decisive?

Only if it matches your workflow. Semantic search, notes-to-rubrics, and live transcription compress real consultation work, but a prescriber who works from paper notes and one desktop will not miss them. The AI gap matters most in high-volume and teleconsultation practices.

For RadarOpus and Synergy users, the alternative to built-in AI is combining a desktop platform with separate transcription or note-taking tools — a manual integration with no native data bridge. Similia's Live Audio Mode (Beta) places AI inside the case-taking session itself, an architectural difference rather than a feature addition. Beta labelling means the feature may change; evaluate it on current behaviour, not on roadmap projections.

Which platform is best for students?

Budget and mobility usually decide it. Similia's Free plan gives students access to classical repertories and semantic search at no cost, with no hardware dependency. RadarOpus and Synergy both publish student licence tiers at reduced pricing, but those still require a machine the student controls. Students likely to shift practices — moving cities, working across clinic and home — will find the device-agnostic cloud model harder to outgrow.

Verdict

Choose RadarOpus for owned depth, Synergy for Mac-practice continuity, Similia for cloud flexibility and AI assistance at the lowest entry cost. Practitioners who want to try the cloud route can use the free Similia plan with classical repertories and semantic search before deciding on Pro.

References

Zeus Soft (2026) RadarOpus product and package pages, radaropus.com, fetched 2026-05.

Synergy Homeopathic (2026) MacRepertory and ReferenceWorks product pages, synergyhomeopathic.com, fetched 2026-05.

Similia (2026) Similia Pricing and Subscription FAQ and product knowledge base, similia.crisp.help, fetched 2026-05.

Similia (2026) Is my patient data secure?, similia.crisp.help, fetched 2026-05.

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